Innate Lymphoid Cells: Immunoregulatory Cells of Mucosal Inflammation
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چکیده
منابع مشابه
Innate Lymphoid Cells in Intestinal Inflammation
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine that encompasses Crohn's disease (CD) and ulcerative colitis. The cause of IBD is unknown, but the evidence suggests that an aberrant immune response toward the commensal bacterial flora is responsible for disease in genetically susceptible individuals. Results from animal models of colitis and human studies in...
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Purpose of review: The purpose of this article is to review recent advances in our understanding of innate lymphoid cell function and to speculate on how these cells may become activated and influence the immune response to allogeneic tissues and cells following transplantation. Recent findings: Innate lymphoid cells encompass several novel cell types whose wide ranging roles in the immune syst...
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Innate lymphoid cells (ILCs) are lymphoid cells that do not express rearranged receptors and have important effector and regulatory functions in innate immunity and tissue remodeling. ILCs are categorized into 3 groups based on their distinct patterns of cytokine production and the requirement of particular transcription factors for their development and function. Group 1 ILCs (ILC1s) produce i...
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The family of innate lymphoid cells (ILCs) consists of a heterogeneous group of cytokine-producing cells that have features in common with adaptive T helper (Th) cells. Cytokines acting through the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathways are key players in both Th and ILC biology. Observations in animal models, supported by evidence from humans, have ...
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innate lymphoid cells (ilcs) are identified as novel population of hematopoietic cells which protect the body by coordinating the innate immune response against a wide range of threats including infections, tissue damages and homeostatic disturbances. ilcs, particularly ilc2 cells, are found throughout the body including the brain. ilcs are morphologically similar to lymphocytes, express and re...
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ژورنال
عنوان ژورنال: European Journal of Inflammation
سال: 2014
ISSN: 2058-7392,2058-7392
DOI: 10.1177/1721727x1401200102